Items from Pompeii, on display
at National Archaeological Museum, Naples
Alexander vs Darius Mosaic. Battle at Issus (brief, with pictures), 333 BC. Alexander the Great vs. King Darius III of Persia. Persian Empire folding, Hellenistic world beginning. Ca. 90 BC-79 CE. Copy of the 4th century BCE Greek painting by Philoxenos of Eretria. Found at Pompeii.
See also
Alexander Sarcophagus photos in Jimuary Istanbul Museum Section
Battle at Issus, 333 BC (long text description)
Alexander of Macedon (timeline), 356-323 BC.
Hear how it may have sounded:
King Darius: "Do'h!"